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Showing 1–3 of 3 results
Advanced filters: Author: Yin Yeng Lee Clear advanced filters

  • Genomic and transcriptomic analysis of lung adenocarcinoma (LUAD) in Asia indicates that Asian LUADs have fewer mutations, lower driver prevalence and fewer copy number alterations than European LUADs.

    • Jianbin Chen
    • Hechuan Yang
    • Weiwei Zhai
    Research
    Nature Genetics
    Volume: 52, P: 177-186

  • EGFR mutant lung adenocarcinoma (LUAD) exhibit diverse clinical outcomes in response to targeted therapies. Here the authors show that these LUADs involve a complex genomic landscape with high intratumor heterogeneity, providing insights into the evolutionary trajectory of oncogene-driven LUAD and potential mediators of EGFR TKI resistance.

    • Rahul Nahar
    • Weiwei Zhai
    • Daniel S. W. Tan
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11