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Showing 1–18 of 18 results

Advanced filters: Author: Yingjie Qu Clear advanced filters

Interpretable deep learning framework for mapping E3–substrate binding interfaces

Protein ubiquitination relies on specific interactions between E3 ligases and substrates. Here, the authors develop MetaESI, a deep learning framework that predicts these interactions and identifies binding interfaces de novo.

Dianke Li
Yuting Zhang
Dong Li
ResearchOpen Access20 May 2026
Nature Communications

P: 1-17
Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Author Correction: High fatigue resistance in a titanium alloy via near-void-free 3D printing

Zhan Qu
Zhenjun Zhang
Zhefeng Zhang
Amendments and Corrections11 Feb 2025
Nature

Volume: 638, P: E48
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
A protein sequence-based deep transfer learning framework for identifying human proteome-wide deubiquitinase-substrate interactions

The specificity of protein deubiquitination relies on deubiquitinase-substrate interactions (DSIs). Here, authors leverage evolutionary information from the proteome to predict DSIs, even with an inadequate training dataset.

Yuan Liu
Dianke Li
Dong Li
ResearchOpen Access28 May 2024
Nature Communications

Volume: 15, P: 1-16
High fatigue resistance in a titanium alloy via near-void-free 3D printing

We successfully rebuild an approximate void-free additive manufacturing microstructure in Ti-6Al-4V titanium alloy by the development of a void-free additive manufacturing processing technique through an understanding of the asynchronism of phase transformation and grain growth.

Zhan Qu
Zhenjun Zhang
Zhefeng Zhang
Research28 Feb 2024
Nature

Volume: 626, P: 999-1004
An improved lightweight algorithm for traffic sign detection

Jia Xu
Yingjie Du
Haojie Du
ResearchOpen Access29 Sept 2025
Scientific Reports

Volume: 15, P: 1-14
Training strategies for semi-supervised remote sensing image captioning

Qimin Cheng
Haojun Cheng
Yuqi Xu
ResearchOpen Access12 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling

Hualin Chen
Wenjie Yang
Zhigang Ji
ResearchOpen Access15 Jul 2023
Cell Death & Disease

Volume: 14, P: 1-14
Aging induces region-specific dysregulation of hormone synthesis in the primate adrenal gland

Wang et al. generate a single nucleus-resolved transcriptomic atlas of primate adrenal aging, with which they demonstrate regional changes in adrenal aging, and establish the role of LDLR in impeding cholesterol uptake and DHEA-S production in aging.

Qiaoran Wang
Xuebao Wang
Weiqi Zhang
Research19 Mar 2024
Nature Aging

Volume: 4, P: 396-413
To investigate the mechanism of Yiwei Decoction in the treatment of premature ovarian insufficiency-related osteoporosis using transcriptomics, network pharmacology and molecular docking techniques

Weisen Fan
Yan Meng
Xin Xiu
ResearchOpen Access03 Nov 2023
Scientific Reports

Volume: 13, P: 1-14
GelMA encapsulating BMSCs-exosomes combined with interference screw or suture anchor promotes tendon-bone healing in a rabbit model

Mingyang Gao
Piqian Zhao
Jing Qu
ResearchOpen Access15 Nov 2024
Scientific Reports

Volume: 14, P: 1-14
SGF29 nuclear condensates reinforce cellular aging

Kaowen Yan
Qianzhao Ji
Guang-Hui Liu
ResearchOpen Access07 Nov 2023
Cell Discovery

Volume: 9, P: 1-21
Multidimensional Bose quantum error correction based on neural network decoder

Haowen Wang
Yunjia Xue
Hongyang Ma
ResearchOpen Access18 Nov 2022
npj Quantum Information

Volume: 8, P: 1-11
Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection

Fei Li
Diping Song
Daniel S. W. Ting
ResearchOpen Access22 Sept 2020
npj Digital Medicine

Volume: 3, P: 1-8
Author Correction: SGF29 nuclear condensates reinforce cellular aging

Kaowen Yan
Qianzhao Ji
Guang-Hui Liu
Amendments and CorrectionsOpen Access15 Feb 2025
Cell Discovery

Volume: 11, P: 1-4
Publisher Correction: SGF29 nuclear condensates reinforce cellular aging

Kaowen Yan
Qianzhao Ji
Guang-Hui Liu
Amendments and CorrectionsOpen Access30 May 2024
Cell Discovery

Volume: 10, P: 1
Author Correction: Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection

Fei Li
Diping Song
Daniel S. W. Ting
Amendments and CorrectionsOpen Access22 Mar 2022
npj Digital Medicine

Volume: 5, P: 1