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Hydrogen sulfide drives horizontal transfer of plasmid-borne antibiotic resistance genes in wastewater ecosystems

This study shows the role of hydrogen sulfide as a driver of plasmid-mediated horizontal gene transfer of antimicrobial resistance genes.

Haining Huang
Lin Lin
Yinguang Chen
Research07 Nov 2025
Nature Water

Volume: 3, P: 1268-1280
Architecture and activation of single-pass transmembrane receptor guanylyl cyclase

Here the authors show the structures of single-pass transmembrane receptor guanylyl cyclase in both apo and hormone-bound states, advancing our understanding of cross-membrane signaling by single-pass transmembrane receptors.

Shian Liu
Alexander M. Payne
Xin-Yun Huang
Research14 Nov 2024
Nature Structural & Molecular Biology

Volume: 32, P: 469-478
NIR-dye bridged human serum albumin reassemblies for effective photothermal therapy of tumor

Human serum albumin (HSA) can be used as a drug delivery material for cancer therapy. Here, the authors report an HSA-based photothermal platform that improves drug loading and photothermal therapeutic performance in breast cancer mouse models.

Zhaoqing Shi
Miaomiao Luo
Hongzhong Chen
ResearchOpen Access17 Oct 2023
Nature Communications

Volume: 14, P: 1-13
Dual-responsive bis-Schiff base fluorescent probe for simultaneous detection of Zn²⁺ and HClO in environmental monitoring and information encryption

Fan Yang
Yinglong Ma
Jing Huang
ResearchOpen Access28 Nov 2025
Scientific Reports

Volume: 15, P: 1-11
Structural basis of agonist specificity of α_1A-adrenergic receptor

α1-adrenergic receptors (α1- AR) play critical roles in the cardiovascular and nervous systems. Here, the authors report molecular insights into the mechanisms underlying the discrimination between α1A-AR and α1B-AR by the agonist A61603.

Minfei Su
Jinan Wang
Xin-Yun Huang
ResearchOpen Access10 Aug 2023
Nature Communications

Volume: 14, P: 1-12
Structures of β₁-adrenergic receptor in complex with Gs and ligands of different efficacies

Su et al. report cryo-EM structures of β₁-adrenergic receptor, Gs and ligands of different efficacies. These complexes have similar overall architecture, but with local conformational differences and different stabilities.

Minfei Su
Navid Paknejad
Xin-Yun Huang
ResearchOpen Access14 Jul 2022
Nature Communications

Volume: 13, P: 1-13
Automated segmentation of brain metastases in magnetic resonance imaging using deep learning in radiotherapy

Ruiping Zhang
Yinglong Liu
Peng Peng
ResearchOpen Access25 Sept 2025
Scientific Reports

Volume: 15, P: 1-11
Carboxyl-modified single-walled carbon nanotubes negatively affect bacterial growth and denitrification activity

Xiong Zheng
Yinglong Su
Haining Huang
ResearchOpen Access10 Jul 2014
Scientific Reports

Volume: 4, P: 1-7
Activatable probes for diagnosing and positioning liver injury and metastatic tumors by multispectral optoacoustic tomography

Optoacoustic tomography has great potential for medical diagnosis and preclinical research. Here they develop near infrared activatable xanthene-based optoacoustic probes for diagnosing and localizing drug-induced liver injury and metastasis in mouse models.

Yinglong Wu
Shuailing Huang
Shuizhu Wu
ResearchOpen Access28 Sept 2018
Nature Communications

Volume: 9, P: 1-13
Antihypertensive treatment effect of two dual therapies according to sodium sensitivity

Qi-Fang Huang
Di Zhang
Jianqiang Xiao
Research06 Oct 2025
Hypertension Research

Volume: 49, P: 340-349
Delayed coastal inundations caused by ocean dynamics post-Hurricane Matthew

Kyungmin Park
Emanuele Di Lorenzo
Fei Ye
ResearchOpen Access02 Jan 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-9
Effects of presenilin-1 familial Alzheimer’s disease mutations on γ-secretase activation for cleavage of amyloid precursor protein

Gaussian accelerated molecular dynamics (GaMD) simulations and biochemical experiments in E.Coli provide mechanistic insight into how Presenilin-1 familial Alzheimer’s disease mutations affect structural dynamics and enzyme-substrate interactions of γ-secretase and APP

Hung N. Do
Sujan Devkota
Yinglong Miao
ResearchOpen Access14 Feb 2023
Communications Biology

Volume: 6, P: 1-14
Distinct binding conformations of epinephrine with α- and β-adrenergic receptors

Jian-Shu Lou
Minfei Su
Xin-Yun Huang
ResearchOpen Access02 Sept 2024
Experimental & Molecular Medicine

Volume: 56, P: 1952-1966
PBK correlates with prognosis, immune escape and drug response in LUAD

Hongyu Ma
Jing Zhang
Chaoqun Lian
ResearchOpen Access22 Nov 2023
Scientific Reports

Volume: 13, P: 1-16
Carbon nanotubes affect the toxicity of CuO nanoparticles to denitrification in marine sediments by altering cellular internalization of nanoparticle

Xiong Zheng
Yinglong Su
Xu Li
ResearchOpen Access09 Jun 2016
Scientific Reports

Volume: 6, P: 1-9

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