Cellobiohydrolases are promising tools in biofuel production by hydrolysing cellulose into cellobiose. Here the authors use optical tweezers to show that Cellobiohydrolase 1 fromTricodermia reeseifunctions processively against moderate load, and likely uses multiple energy sources to fuel each step along the cellulose fibre.
- Sonia K. Brady
- Sarangapani Sreelatha
- Matthew J Lang