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Scientific Reports (5)
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Showing 1–15 of 15 results

Advanced filters: Author: Yinsheng Wu Clear advanced filters

Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence

Little is known about the role of glycolysis in cellular senescence. Here, authors report that glycolysis-derived serine biosynthesis activates PKM2 to phosphorylate histone H3T11, prevent cell senescence, and promote healthy aging.

Yinsheng Wu
Lixu Tang
Xilan Yu
ResearchOpen Access10 Mar 2023
Nature Communications

Volume: 14, P: 1-21
IL-27 alleviates high-fat diet-induced obesity and metabolic disorders by inhibiting adipogenesis via activating HDAC6

Obesity arises from an imbalance between adipogenesis and adipocyte thermogenesis. IL-27 suppresses adipogenesis, prevents weight gain, and improves glucose and lipid metabolic homeostasis in high-fat diet obese mice.

Yinsheng Zhong
Shujun Yang
Tong Wang
ResearchOpen Access19 Mar 2025
Communications Biology

Volume: 8, P: 1-12
A wireless and battery-less implant for multimodal closed-loop neuromodulation in small animals

A tether-less and battery-less implant allows for the recording of electroencephalograms, electromyograms and body temperature in freely moving small animals, and for closed-loop neuromodulation via optogenetics and pharmacology.

Wei Ouyang
Wei Lu
John A. Rogers
Research27 Apr 2023
Nature Biomedical Engineering

Volume: 7, P: 1252-1269
A geospatial dataset of PFOS and PFOA occurrence records in China’s multi-media environments (2021–2024)

Xiaolong Wu
Yiyang Guo
Sen Li
ResearchOpen Access02 Sept 2025
Scientific Data

Volume: 12, P: 1-9
The SESAME complex regulates cell senescence through the generation of acetyl-CoA

Using budding yeast and human endothelial cells, Li et al. find that increased synthesis of acetyl-CoA in the nucleus promotes histone acetylation at subtelomeric regions, thus leading to telomere silencing defects and cellular senescence.

Wanping Chen
Xilan Yu
Shanshan Li
Research28 Jun 2021
Nature Metabolism

Volume: 3, P: 983-1000
N⁶-methyladenine in DNA antagonizes SATB1 in early development

The DNA modification N⁶-methyladenine regulates gene expression during mouse trophoblast development by depositing at the boundaries of active chromatin and preventing its spread by antagonizing the chromatin organizer SATB1.

Zheng Li
Shuai Zhao
Andrew Z. Xiao
Research15 Jul 2020
Nature

Volume: 583, P: 625-630
Er³⁺-doped transparent glass ceramics containing micron-sized SrF₂ crystals for 2.7 μm emissions

Yiguang Jiang
Jintai Fan
Long Zhang
ResearchOpen Access19 Jul 2016
Scientific Reports

Volume: 6, P: 1-8
Management and survival trends for diffuse gliomas diagnosed at a single neurooncology center in China during 2000 to 2020

Depei Li
Yinsheng Chen
Zhongping Chen
ResearchOpen Access12 Apr 2025
Scientific Reports

Volume: 15, P: 1-11
Impact of environmental and operational stress on defect formation in China’s high-speed rail subgrades

Subgrade defects in China’s high-speed rail are affected by geomorphology, geology, land use, and operation stress, according to structural equation modeling.

Jinchen Wang
Yinsheng Zhang
Sen Li
ResearchOpen Access22 Apr 2025
Communications Earth & Environment

Volume: 6, P: 1-13
Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability

Xinyu Zhang
Qi Yu
Shanshan Li
ResearchOpen Access11 Jul 2023
Cell Discovery

Volume: 9, P: 1-25
A dataset of multi-level street-block divisions of 985 cities worldwide

Jintong Tang
Liyan Xu
Yu Liu
ResearchOpen Access19 Mar 2025
Scientific Data

Volume: 12, P: 1-15
Post-20^th century near-steady state of Batura Glacier: observational evidence of Karakoram Anomaly

Haifeng Gao
Xiaojuan Zou
Guocai Zhu
ResearchOpen Access22 Jan 2020
Scientific Reports

Volume: 10, P: 1-10
Comparative physiological and transcriptomic analysis of pear leaves under distinct training systems

Zheng Liu
Liyuan An
Zhongqi Qin
ResearchOpen Access03 Nov 2020
Scientific Reports

Volume: 10, P: 1-15
Baicalin modulates NF-κB and NLRP3 inflammasome signaling in porcine aortic vascular endothelial cells Infected by Haemophilus parasuis Causing Glässer’s disease

Shulin Fu
Huashan Liu
Chien-An Andy Hu
ResearchOpen Access16 Jan 2018
Scientific Reports

Volume: 8, P: 1-14
Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair

Steven T. Sizemore
Manchao Zhang
Fen Xia
ResearchOpen Access08 Oct 2018
Cell Research

Volume: 28, P: 1090-1102