Thymic epithelial cells (TECs) are essential for T cell development but how they develop from progenitors in humans is difficult to study. Here authors set up an in vitro system for thymus organogenesis in which induced pluripotent stem cells give rise to mature and diverse TECs that fully support T cell differentiation.
- Yann Pretemer
- Yuxian Gao
- Yoko Hamazaki
