Bacillus thuringiensis Vip3 (Vegetative Insecticidal Protein 3) toxins are widely used in biotech crops to control Lepidopteran pests. Here authors present the cryo-EM structures of the protoxin and the protease-activated state of Vip3Aa which shed light on the molecular basis for Vip3 activation.
- Rafael Núñez-Ramírez
- Juanjo Huesa
- Ernesto Arias-Palomo