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Showing 1–6 of 6 results
Advanced filters: Author: Yonatan B. Tzur Clear advanced filters

  • RNA-binding FBF proteins control germline stem cell differentiation. Here, the authors show that three long non-coding RNAs bind, condense, and thus inhibit FBFs to promote the transition of germline stem cells into meiosis.

    • Roni Falk
    • Noa Gilad
    • Yonatan B. Tzur
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • During meiotic cell division, chromosome pairs exchange genetic material in a tightly controlled crossover process. Higher-order chromosome structure may regulate this genetic reshuffling at two distinct stages of meiosis.

    • Yonatan B. Tzur
    • Monica P. Colaiácovo
    News & Views
    Nature
    Volume: 462, P: 46-47

  • RNA polymerase III–driven single guide RNA and a germ line promoter–driven expression of Cas9 enzyme allow heritable, targeted genome modifications in Caenorhabditis elegans.

    • Ari E Friedland
    • Yonatan B Tzur
    • John A Calarco
    Research
    Nature Methods
    Volume: 10, P: 741-743

  • During meiosis, sex chromosomes show silenced gene expression that is disrupted when translocated to autosomes. Here, the authors engineer C. elegans with bisected X chromosomes and see active transcription in gonads, indicating continuity of sex chromosomes promotes silencing.

    • Yisrael Rappaport
    • Hanna Achache
    • Yonatan B. Tzur
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • The SUN-domain family of nuclear envelope proteins interacts with KASH-domain proteins, which are also nuclear envelope proteins, to form 'bridges' across the inner and outer nuclear membranes. SUN-domain proteins are now proposed to provide a mechanical connection between the nucleoskeleton and the cytoskeleton.

    • Yonatan B. Tzur
    • Katherine L. Wilson
    • Yosef Gruenbaum
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 7, P: 782-788