The cell adhesion and growth were studied on vertically aligned silicon nanowires with different diameter. Varying the diameter of nanowires affected their elasticity, resulting in a difference in cell morphology and adhesion. The formation of focal adhesion and anisotropic cell growth was promoted on thin silicon nanowires. Fluorescence analysis demonstrated that the cytoskeletal actin dynamics was affected by the mechanical tension of elastic nanotopography.
- Yi-Seul Park
- Seo Young Yoon
- Jin Seok Lee
