Nature Search

Triggering neural differentiation of ES cells by subtype switching of importin-α

Noriko Yasuhara
Noriko Shibazaki
Yoshihiro Yoneda
Research10 Dec 2006
Nature Cell Biology

Volume: 9, P: 72-79
Nocistatin, a peptide that blocks nociceptin action in pain transmission

Emiko Okuda-Ashitaka
Toshiaki Minami
Seiji Ito
Research19 Mar 1998
Nature

Volume: 392, P: 286-289
Primordial aqueous alteration recorded in water-soluble organic molecules from the carbonaceous asteroid (162173) Ryugu

In this study, the authors report primordial aqueous alteration signatures in water-soluble organic molecules from the carbonaceous asteroid Ryugu. This provides evidence o coevolutionary aqueous alteration between water and organics in this asteroid.

Yoshinori Takano
Hiroshi Naraoka
Shogo Tachibana
ResearchOpen Access10 Jul 2024
Nature Communications

Volume: 15, P: 1-15
Extraterrestrial hexamethylenetetramine in meteorites—a precursor of prebiotic chemistry in the inner solar system

This manuscript tackles the origin of organic molecules in carbonaceous meteorites. Identifying hexamethylenetetramine in three carbonaceous meteorites, the authors propose formation from ammonia and formaldehyde by photochemical and thermal reactions in the interstellar medium, followed by the incorporation into planetary systems.

Yasuhiro Oba
Yoshinori Takano
Shogo Tachibana
ResearchOpen Access07 Dec 2020
Nature Communications

Volume: 11, P: 1-8
Soluble organic matter Molecular atlas of Ryugu reveals cold hydrothermalism on C-type asteroid parent body

The molecular atlas of soluble organic compounds from Ryugu shows unprecedented molecular complexity and diversity resulting from alteration on a low temperature, water rich parent body.

Philippe Schmitt-Kopplin
Norbert Hertkorn
Yasuhiro Oba
ResearchOpen Access16 Oct 2023
Nature Communications

Volume: 14, P: 1-9
Chemical evolution of primordial salts and organic sulfur molecules in the asteroid 162173 Ryugu

The asteroid Ryugu samples are by far the freshest extraterrestrial carbonaceous material. The authors report soluble ions and organic sulfur molecules linked with primordial brine and prebiotic organic evolution of the primitive asteroid.

Toshihiro Yoshimura
Yoshinori Takano
Yuki Kimura
ResearchOpen Access18 Sept 2023
Nature Communications

Volume: 14, P: 1-11
Identifying the wide diversity of extraterrestrial purine and pyrimidine nucleobases in carbonaceous meteorites

All DNA/RNA nucleobases were identified in carbonaceous meteorites. Having been provided to the early Earth as a component in carbonaceous meteorites, these molecules might have played a role for the emergence of genetic functions in early life.

Yasuhiro Oba
Yoshinori Takano
Hiroshi Naraoka
ResearchOpen Access26 Apr 2022
Nature Communications

Volume: 13, P: 1-10
SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication

The SARS-CoV-2 ORF6, an antagonist of interferon-mediated antiviral signaling, directly binds to STAT1 and prevents its nuclear localization.

Yoichi Miyamoto
Yumi Itoh
Masahiro Oka
ResearchOpen Access19 May 2022
Communications Biology

Volume: 5, P: 1-15
JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis

Demethylase JMJD1A activates thermogenesis-related target genes in response to β-adrenergic hormones. Here, the authors show that phosphorylation of JMJD1A at S265 increases its interaction with the SWI/SNF chromatin remodeler, leading to long-range chromatin interactions and target gene activation.

Yohei Abe
Royhan Rozqie
Juro Sakai
ResearchOpen Access07 May 2015
Nature Communications

Volume: 6, P: 1-14
Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch

JMJD1A is essential for thermogenic gene induction in brown adipose tissue. Here the authors show that white adipose tissue beige-ing requires both β-adrenergic-dependent phosphorylation of S265 and demethylation activity of JMJD1A while brown adipose tissue-driven thermogenesis requires β-adrenergic dependent phosphorylation of S265 but is independent of H3K9me2 demethylation.

Yohei Abe
Yosuke Fujiwara
Juro Sakai
ResearchOpen Access19 Apr 2018
Nature Communications

Volume: 9, P: 1-16
Differential brain volume between obese and underweight cognitively normal older adults with frailty in the JPSC-AD

Naoki Ishizuka
Hiroshi Akasaka
Yutaka Kiyohara
ResearchOpen Access04 Jun 2025
Scientific Reports

Volume: 15, P: 1-12
High moisture confluence in Japan Sea polar air mass convergence zone captured by hourly radiosonde launches from a ship

Yoshihiro Tachibana
Meiji Honda
Yuji Kashino
ResearchOpen Access23 Dec 2022
Scientific Reports

Volume: 12, P: 1-13
Warm hole in Pacific Arctic sea ice cover forced mid-latitude Northern Hemisphere cooling during winter 2017–18

Yoshihiro Tachibana
Kensuke K. Komatsu
Yuta Ando
ResearchOpen Access03 Apr 2019
Scientific Reports

Volume: 9, P: 1-12
Poleward upgliding Siberian atmospheric rivers over sea ice heat up Arctic upper air

Kensuke K. Komatsu
Vladimir A. Alexeev
Yoshihiro Tachibana
ResearchOpen Access13 Feb 2018
Scientific Reports

Volume: 8, P: 1-15
Sea ice records over more than a century at an observatory facing the Okhotsk coast of Hokkaido, Japan

Takahiro Toyoda
Kento Tsukagawa
Masao Ishii
ResearchOpen Access13 Jun 2025
Scientific Data

Volume: 12, P: 1-10
Serum high-sensitivity C-reactive protein and dementia in a community-dwelling Japanese older population (JPSC-AD)

Ayumi Tachibana
Jun-ichi Iga
Yutaka Kiyohara
ResearchOpen Access28 Mar 2024
Scientific Reports

Volume: 14, P: 1-9
Green tea consumption and cerebral white matter lesions in community-dwelling older adults without dementia

Shutaro Shibata
Moeko Noguchi-Shinohara
Yutaka Kiyohara
ResearchOpen Access07 Jan 2025
npj Science of Food

Volume: 9, P: 1-8
Impact of standard-dose dipeptidyl peptidase-4 inhibitors on the incidence of graft-versus-host disease after allogeneic hematopoietic cell transplantation

Shun-ichi Kimura
Hiroaki Shimizu
Yoshinobu Kanda
Correspondence26 Dec 2022
Bone Marrow Transplantation

Volume: 58, P: 452-455
Glucose metabolism and smaller hippocampal volume in elderly people with normal cognitive function

Ayano Shima
Moeko Noguchi-Shinohara
Yutaka Kiyohara
ResearchOpen Access09 Sept 2024
npj Aging

Volume: 10, P: 1-10
Author Correction: Warm hole in Pacific Arctic sea ice cover forced mid-latitude Northern Hemisphere cooling during winter 2017–18

Yoshihiro Tachibana
Kensuke K. Komatsu
Yuta Ando
Amendments and CorrectionsOpen Access17 Mar 2020
Scientific Reports

Volume: 10, P: 1-2

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