Central poststroke pain is not a rare consequence of stroke, but current pharmacological treatment options are limited and have little benefit. In this Review, the authors reconsider central poststroke pain as a network reorganization disorder, providing a framework to better understand the pathogenesis of the condition. In this context, they discuss the use of invasive and noninvasive neurostimulation to provide pain relief through modulation of network nodes, either as an alternative to or in combination with pharmacological treatments.
- Koichi Hosomi
- Ben Seymour
- Youichi Saitoh