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Showing 1–2 of 2 results
Advanced filters: Author: Young-Min Soh Clear advanced filters

  • SARS-CoV-2 infection can cause coagulopathic events. Kuhn et al. show by cryo-ET how the Spike protein impacts platelet morphology by binding to the platelet surface, leading to micro-activation; and investigate integrin as possible point of contact.

    • Christopher Cyrus Kuhn
    • Nirakar Basnet
    • Naoko Mizuno
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Prokaryotic condensins usually comprise an SMC homodimer, kleisin ScpA and ScpB. Structural and functional analyses of Bacillus subtilis condesin reveal an asymmetric bridge in which the termini of ScpA bind to distinct regions in each of the two SMC monomers. The findings suggest that the basic architecture for the tripartite condensin ring evolved before the emergence of eukaryotes.

    • Frank Bürmann
    • Ho-Chul Shin
    • Stephan Gruber
    Research
    Nature Structural & Molecular Biology
    Volume: 20, P: 371-379