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Showing 1–5 of 5 results
Advanced filters: Author: Yousi Fu Clear advanced filters
  • A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent physiology.

    • Tae Hyung Won
    • Mohammad Arifuzzaman
    • Frank C. Schroeder
    Research
    Nature
    Volume: 638, P: 216-224
  • Acyltransferase activity of the enzyme bile salt hydrolase is identified and shown to mediate microbial bile acid conjugation, diversifying the bile acid pool and expanding their role in gut physiology.

    • Douglas V. Guzior
    • Maxwell Okros
    • Robert A. Quinn
    Research
    Nature
    Volume: 626, P: 852-858
  • In an inter-laboratory study, the authors compare the accuracy and performance of three optical density calibration protocols (colloidal silica, serial dilution of silica microspheres, and colony-forming unit (CFU) assay). They demonstrate that serial dilution of silica microspheres is the best of these tested protocols, allowing precise and robust calibration that is easily assessed for quality control and can also evaluate the effective linear range of an instrument.

    • Jacob Beal
    • Natalie G. Farny
    • Jiajie Zhou
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-29