HIV replication has been shown previously to be inhibited by combinations of T cells and NK cells according to HLA and KIR haplotype. Here the authors consider a combination of KIR2DL2+ NK and HLA-C*12:02-restricted T cells and clarify how a specific HIV pol escape mutant facilitates virus control by KIR2DL2+ NK cells.
- Takayuki Chikata
- Kimiko Kuroki
- Masafumi Takiguchi
