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Advanced filters: Author: Yuanhui Qiu Clear advanced filters

Simultaneous profiling of RNA isoforms and chromatin accessibility of single cells of human retinal organoids

Here, the authors present scRICA-seq, which is capable of profiling isoforms and chromatin accessibility for up to 10,000 single cells in a single run. By applying this method to human retinal organoids, they construct a multi-omic cell atlas.

Shuyao Zhang
Yuhua Xiao
Youjin Hu
ResearchOpen Access13 Sept 2024
Nature Communications

Volume: 15, P: 1-13
Single-cell RNA cap and tail sequencing (scRCAT-seq) reveals subtype-specific isoforms differing in transcript demarcation

Most single-cell RNA sequencing methods have limited ability to profile the transcriptome at isoform resolution. Here the authors develop scRCAT-seq to characterize the 5′- and 3′-ends of transcripts in single cells, and identify cell-type specific alternative transcript isoforms.

Youjin Hu
Jiawei Zhong
Yizhi Liu
ResearchOpen Access13 Oct 2020
Nature Communications

Volume: 11, P: 1-11
The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation

Jihui Qiu
Guang Shi
Jiemin Wong
Research15 Jun 2010
Cell Research

Volume: 20, P: 908-918

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