The role of phosphorylated CTD interacting factor-1 (PCIF1) in neuropathic pain-anxiety comorbidity remains elusive. Here, authors identify the SERBP1–PCIF1 complex, which targets m6Am modification in glutamatergic neurons of the S1HL, as a potential therapeutic target.
- Yue Huang
- Gan Ma
- Zhi-Qiang Pan