Qi Ding, Ferzin Sethna et al. perform a computational analysis of the transcriptome profile of Fmr1−/− neurons and identify trifluoperazine as potential therapeutic agent against Fragile X Syndrome. Next, they show that low doses of trifluoperazine ameliorate some of the behavioral and molecular phenotypes present in Fmr1−/− mice.
- Qi Ding
- Ferzin Sethna
- Hongbing Wang
