Integration and design of existing function units into specialized architectures might show combined and even improved performances of the original components. Here we describe a serial of synthetic antibacterial complexes composed of melittin, a natural antimicrobial peptide, and poly(ethylene glycol), a clinical available agent, as building blocks, which show potent and architecture-modulated antibacterial activity against multidrug-resistant pathogens and decreased cytotoxicity.
- Bing Yuan
- Jiaojiao Liu
- Zhenhui Kang
