Nature Search

Hydrops fetalis due to loss of function of hNav1.4 channel via compound heterozygous variants

Tomoya Kubota
Miho Nagata
Masanori P. Takahashi
ResearchOpen Access21 Aug 2024
Journal of Human Genetics

Volume: 70, P: 3-8
A rare PRIMER cell state in plant immunity

The development of a molecularly defined spatiotemporal atlas of pathogen-infected Arabidopsis thaliana leaves reveals specific cell states that have distinct roles in plant immunity.

Tatsuya Nobori
Alexander Monell
Joseph R. Ecker
ResearchOpen Access08 Jan 2025
Nature

Volume: 638, P: 197-205
The genome sequence and structure of rice chromosome 1

Takuji Sasaki
Takashi Matsumoto
Takashi Gojobori
ResearchOpen Access21 Nov 2002
Nature

Volume: 420, P: 312-316
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells

Spermatogonia establishment in the fetal and postnatal period is essential for spermatozoa production. Here the authors present a protocol for in vitro reconstitution of human prospermatogonial specification and perform single cell RNA-sequencing to delineate lineage trajectories.

Young Sun Hwang
Shinnosuke Suzuki
Kotaro Sasaki
ResearchOpen Access09 Nov 2020
Nature Communications

Volume: 11, P: 1-17
Quantitative diagnostic imaging of cancer tissues by using phosphor-integrated dots with ultra-high brightness

Kohsuke Gonda
Mika Watanabe
Noriaki Ohuchi
ResearchOpen Access08 Aug 2017
Scientific Reports

Volume: 7, P: 1-13
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Renin–angiotensin–aldosterone system has a pivotal role in cognitive impairment

Shusuke Yagi
Masashi Akaike
Masataka Sata
Reviews23 May 2013
Hypertension Research

Volume: 36, P: 753-758
Association between the extent of house collapse and urine sodium-to-potassium ratio of victims affected by the 2011 Great East Japan Earthquake and Tsunami: a cross-sectional study

Takahiro Mikami
Kozo Tanno
Makoto Sasaki
ResearchOpen Access17 Feb 2023
Hypertension Research

Volume: 46, P: 1247-1256
dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project

Soichi Ogishima
Satoshi Nagaie
Masayuki Yamamoto
ResearchOpen Access10 Dec 2021
Human Genome Variation

Volume: 8, P: 1-8
Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas

Keisuke Kataoka
Hiroaki Miyoshi
Seishi Ogawa
ResearchOpen Access25 Jan 2019
Leukemia

Volume: 33, P: 1687-1699
Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling

Yosaku Watatani
Yasuharu Sato
Keisuke Kataoka
ResearchOpen Access15 May 2019
Leukemia

Volume: 33, P: 2867-2883
Nucleosome destabilization by nuclear non-coding RNAs

The Eleanor cluster of non-coding RNAs is localised upstream of estrogen receptor-α (ESR1) gene locus in estrogen-deprived breast cancer cells. Fujita et al find that RNA fragments of Eleanor2 and of other non-coding RNAs are able to destabilise nucleosomes in vitro, suggesting a role in transcriptional regulation.

Risa Fujita
Tatsuro Yamamoto
Hitoshi Kurumizaka
ResearchOpen Access11 Feb 2020
Communications Biology

Volume: 3, P: 1-11
BRD4 promotes metastatic potential in oral squamous cell carcinoma through the epigenetic regulation of the MMP2 gene

Tatsuro Yamamoto
Akiyuki Hirosue
Hideki Nakayama
ResearchOpen Access05 Jun 2020
British Journal of Cancer

Volume: 123, P: 580-590
Novel bio-based flexible bisphenol epoxy resin derived from cashew nut shell liquid

Cashew nut shell liquid (CNSL) is a natural phenolic compounds that is non-edible biomass. A novel diglycidyl ether (BCNDGE) derived from CNSL was synthesized and used as a building block to formulate an epoxy resin. Epoxy resins were cured from BCNDGE and commercial diglycidyl ether (BPADGE) with acid anhydride hardener. BCNDGE content improved the thermal stability and flexibility of the epoxy compared with commercial BPADGE-based epoxy. Hence, BCNDGE is a promising novel diglycidyl ether candidate with high biomass content to act as an alternative to petroleum-based chemicals for epoxy resins.

Yuka Yokoyama
Tatsuya Yasui
Shinji Kanehashi
Research28 Apr 2023
Polymer Journal

Volume: 55, P: 859-867
Clinical and genetic features of cystic fibrosis in Japan

Yuka Kozawa
Akiko Yamamoto
Hiroshi Ishiguro
Research22 May 2023
Journal of Human Genetics

Volume: 68, P: 671-680

Search

Hydrops fetalis due to loss of function of hNav1.4 channel via compound heterozygous variants

A rare PRIMER cell state in plant immunity

The genome sequence and structure of rice chromosome 1

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells

Quantitative diagnostic imaging of cancer tissues by using phosphor-integrated dots with ultra-high brightness

Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Renin–angiotensin–aldosterone system has a pivotal role in cognitive impairment

Association between the extent of house collapse and urine sodium-to-potassium ratio of victims affected by the 2011 Great East Japan Earthquake and Tsunami: a cross-sectional study

dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project

Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas

Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling

Nucleosome destabilization by nuclear non-coding RNAs

BRD4 promotes metastatic potential in oral squamous cell carcinoma through the epigenetic regulation of the MMP2 gene

Novel bio-based flexible bisphenol epoxy resin derived from cashew nut shell liquid

Clinical and genetic features of cystic fibrosis in Japan

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