Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Yumi Xuan Clear advanced filters

  • Human guanylate kinase (GMPK) is the sole enzyme for GDP biosynthesis contributing to antiviral prodrug activation and tumorigenesis. Here, authors profile the ligand-specific conformations of human GMPK along with the reversible catalytic pathway.

    • Lei Wang
    • Zihuan Li
    • Ke Ruan
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12

  • Pentamidine and melarsoprol are drugs used to treat sleeping sickness caused by Trypanosoma brucei. Here, authors present cryo-EM structures of TbAQP2 with molecular dynamic simulations, revealing mechanisms shaping substrate specificity and drug permeation.

    • Wanbiao Chen
    • Rongfeng Zou
    • Chongyuan Wang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-10