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Nature Chemical Biology (2)
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Showing 1–4 of 4 results

Advanced filters: Author: Yuri Tomabechi Clear advanced filters

Amyloid conformation-dependent disaggregation in a reconstituted yeast prion system

Real-time fluorescence imaging analysis with a reconstitution system revealed binding dynamics of Hsp104/Ssa1/Sis1 chaperones to Sup35 amyloid and two distinct modes of amyloid disaggregation, fragmentation and dissolution.

Yoshiko Nakagawa
Howard C.-H. Shen
Motomasa Tanaka
Research17 Feb 2022
Nature Chemical Biology

Volume: 18, P: 321-331
Chemical reversal of abnormalities in cells carrying mitochondrial DNA mutations

Tryptolinamide (TLAM) is a small molecule compound that inhibits phosphofructokinase-1 activity and rescues the metabolic defects of patient-derived induced pluripotent stem cell lines with mutated mitochondrial DNA.

Hiroki Kobayashi
Hideyuki Hatakeyama
Minoru Yoshida
Research09 Nov 2020
Nature Chemical Biology

Volume: 17, P: 335-343
Protein stabilization utilizing a redefined codon

Kazumasa Ohtake
Atsushi Yamaguchi
Kensaku Sakamoto
ResearchOpen Access18 May 2015
Scientific Reports

Volume: 5, P: 1-6
Structural basis for CRMP2-induced axonal microtubule formation

Shinsuke Niwa
Fumio Nakamura
Ryo Nitta
ResearchOpen Access06 Sept 2017
Scientific Reports

Volume: 7, P: 1-17