Peptide synthesis on the ribosome can be blocked by certain peptide motifs. Here, Ando et al. identify E. coli ribosome arrest peptide PepNL. PepNL forms a mini-hairpin to block translation termination and stop codon readthrough counters this stalling.
- Yushin Ando
- Akinao Kobo
- Yuhei Chadani
