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Scientific Reports (2)
Communications Biology (1)

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Showing 1–3 of 3 results

Advanced filters: Author: Yuu Usui Clear advanced filters

CCDC141 is a Connectin/Titin and Nesprin-1 binding protein that adapts cardiomyocytes to mechanical stress

CCDC141 modulates cardiac mechanoadaptation via Connectin/titin and Nesprin-1. Its loss disrupts mitochondrial and Ca²⁺ dynamics, impairs nuclear integrity, and heightens susceptibility to stress-induced heart failure and arrhythmias.

Akira Hanashima
Misaki Kimoto
Satoshi Mohri
ResearchOpen Access26 Nov 2025
Communications Biology

Volume: 8, P: 1-13
Cartilaginous fish and mammalian connectin evolved independently from an ancestral bony fish-like structure

Akira Hanashima
Yoshihiro Ujihara
Satoshi Mohri
ResearchOpen Access09 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics

Ken Hashimoto
Momoko Ohira
Satoshi Mohri
ResearchOpen Access14 Jun 2024
Scientific Reports

Volume: 14, P: 1-19