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Showing 1–7 of 7 results
Advanced filters: Author: Yves Barral Clear advanced filters

  • In budding yeast ageing factors are retained in the mother cell, ensuring that the newly formed bud remains young. It is shown that a septin-dependent barrier forms in the nuclear envelope, which prevents pre-existing nuclear pores and other ageing factors from moving into the newly formed bud. These results demonstrate the importance of the nuclear envelope in ageing in yeast cells.

    • Zhanna Shcheprova
    • Sandro Baldi
    • Yves Barral
    Research
    Nature
    Volume: 454, P: 728-734

  • How do septins, GTP-binding proteins, function in a wide range of cellular processes, such as cell division, cytoskeletal organization and membrane remodelling? Electron microscopy and crystallographic studies provide a glimpse into septin-complex assembly that could answer this question.

    • Christine S. Weirich
    • Jan P. Erzberger
    • Yves Barral
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 9, P: 478-489

  • In yeast, anaphase defects can trigger activation of the NoCut checkpoint, resulting in delayed cytokinesis. The Ilp1/aurora kinase localizes to the spindle midzone and monitors chromatin segregation, thus acting as a chromatin sensor.

    • Manuel Mendoza
    • Caren Norden
    • Yves Barral
    Research
    Nature Cell Biology
    Volume: 11, P: 477-483

  • Asymmetrical cell division helps to maintain cellular heterogeneity in the T cell compartment. Here the authors examine the differential immune responses built by naive and virtual memory T cells from young and aged individuals, and explore the effect of mTOR inhibition on asymmetrical cell division and memory formation.

    • Mariana Borsa
    • Niculò Barandun
    • Annette Oxenius
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12