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Showing 1–8 of 8 results
Advanced filters: Author: Zachary C. Cordero Clear advanced filters

  • Materials for extreme environments can help to protect people, structures and the planet. Extreme temperatures in aeroplane engines, hypervelocity micrometeoroid impacts on satellites, high-speed machining of ceramics and strong radiation doses in nuclear reactors are just some examples of extreme conditions that materials need to withstand. In this Viewpoint, experts working on materials for different types of extreme environments discuss the most exciting advances, opportunities and bottlenecks in their fields.

    • Suhas Eswarappa Prameela
    • Tresa M. Pollock
    • Lori Graham-Brady
    Reviews
    Nature Reviews Materials
    Volume: 8, P: 81-88

  • Macrocyclic peptides are promising scaffolds for chemical tools and potential therapeutics, but their synthesis is currently difficult. Here, the authors report the characterization of Ulm16, a peptide cyclase of the penicillin-binding protein (PBP)-type class of thioesterases, that catalyzes head-to-tail macrolactamization of nonribosmal peptides of 4–6 amino acids in length.

    • Zachary L. Budimir
    • Rishi S. Patel
    • Elizabeth I. Parkinson
    Research
    Nature Chemical Biology
    Volume: 20, P: 120-128

  • The genomic and epigenomic landscape during metastasis in osteosarcoma remains to be investigated. Here, functional and pharmacological studies identify the dynamic epigenomic changes and gene vulnerabilities during the formation of osteosarcoma tumours in the lung microenvironment.

    • W. Dean Pontius
    • Ellen S. Hong
    • Peter C. Scacheri
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • The ability of marine bacteria to direct their movement in response to chemical gradients influences inter-species interactions, nutrient turnover, and ecosystem productivity. Here, Clerc et al. show that marine bacteria are strongly attracted to algal polysaccharides, and this chemotactic behaviour is enhanced by dimethylsulfoniopropionate (DMSP), a ubiquitous algal metabolite.

    • Estelle E. Clerc
    • Jean-Baptiste Raina
    • Roman Stocker
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • In an inter-laboratory study, the authors compare the accuracy and performance of three optical density calibration protocols (colloidal silica, serial dilution of silica microspheres, and colony-forming unit (CFU) assay). They demonstrate that serial dilution of silica microspheres is the best of these tested protocols, allowing precise and robust calibration that is easily assessed for quality control and can also evaluate the effective linear range of an instrument.

    • Jacob Beal
    • Natalie G. Farny
    • Jiajie Zhou
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-29