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Erratum: Activin A programs the differentiation of human T_FH cells

Michela Locci
Jennifer E Wu
Shane Crotty
Amendments and Corrections20 Sept 2016
Nature Immunology

Volume: 17, P: 1235
YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution

The molecular mechanisms underlying tumour initiation remain elusive. Here, the authors use spatiotemporally controlled oncogene activation and tumour suppressor inhibition with multi-omics to unveil the role of YAP-mediated oral epithelial progenitor cell reprogramming into tumour-initiating cells.

Farhoud Faraji
Sydney I. Ramirez
J. Silvio Gutkind
ResearchOpen Access08 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Nuclear morphology is shaped by loop-extrusion programs

In neutrophil progenitor cells, stopping the process of loop extrusion by depleting nipped-B-like protein (NIPBL) results in the assembly of polymorphonuclear structures and the activation of a neutrophil-specific gene program.

Indumathi Patta
Maryam Zand
Cornelis Murre
Research14 Feb 2024
Nature

Volume: 627, P: 196-203
Human coronavirus OC43-elicited CD4⁺ T cells protect against SARS-CoV-2 in HLA transgenic mice

The origin of SARS-CoV-2 cross-reactive T cells in unexposed humans is unclear. Here, the authors use HLA transgenic mouse models of sequential infections with human coronavirus OC43 and SARSCoV-2 and show that OC43 elicits cross-protective immunity against SARS-CoV-2, which partially depends on CD4 + T cells.

Rúbens Prince dos Santos Alves
Julia Timis
Sujan Shresta
ResearchOpen Access26 Jan 2024
Nature Communications

Volume: 15, P: 1-20
Microfluidics-based side view flow chamber reveals tether-to-sling transition in rolling neutrophils

Alex Marki
Edgar Gutierrez
Klaus Ley
ResearchOpen Access30 Jun 2016
Scientific Reports

Volume: 6, P: 1-8
Bacterial colonization factors control specificity and stability of the gut microbiota

Germ-free mice mono-associated with a single species of Bacteroides are found to be resistant to further colonization by the same, but not different, species; a unique class of polysaccharide utilization loci that is required for the penetration of the colonic mucus and colonization of the crypt channel niche is discovered that explains this observed species-specific saturable colonization.

S. Melanie Lee
Gregory P. Donaldson
Sarkis K. Mazmanian
Research18 Aug 2013
Nature

Volume: 501, P: 426-429
IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis

Innate immune responses are regulated in the intestine to prevent excessive inflammation. Here the authors demonstrate a pivotal role for intestinal macrophages that constitutively produce IL-10 in controlling excessive innate immune activation and preventing tissue damage after an acute bacterial infection.

Petra Krause
Venetia Morris
Masako Murai
Research11 May 2015
Nature Communications

Volume: 6, P: 1-12
Neutrophil recruitment limited by high-affinity bent β₂ integrin binding ligand in cis

Integrin β₂ attachment regulates inflammation via effects on neutrophil rolling and extravasation through sequential integrin extension then headpiece opening. Here the authors show an alternative open headpiece prior to extension stabilized in cisby ICAM-1 that limits neutrophil adhesion.

Zhichao Fan
Sara McArdle
Klaus Ley
ResearchOpen Access31 Aug 2016
Nature Communications

Volume: 7, P: 1-14
Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation

Stress can induce expression of norepinephrine, which can enhance neuroinflammation. Shaked, Hedrick and colleagues show that the transcriptional repressor Nr4a1 limits this stress-induced response by suppressing expression of tyrosine hydroxylase required for the synthesis of norepinephrine.

Iftach Shaked
Richard N Hanna
Catherine C Hedrick
Research01 Dec 2015
Nature Immunology

Volume: 16, P: 1228-1234
Activin A programs the differentiation of human T_FH cells

Crotty and colleagues identify activin A as a regulator of human T_FH cell differentiation. The effects of activin A show evolutionary divergence.

Michela Locci
Jennifer E Wu
Shane Crotty
Research04 Jul 2016
Nature Immunology

Volume: 17, P: 976-984
An integrin αEβ7-dependent mechanism of IgA transcytosis requires direct plasma cell contact with intestinal epithelium

Mauricio Guzman
Luke R. Lundborg
Jesús Rivera-Nieves
ResearchOpen Access20 Aug 2021
Mucosal Immunology

Volume: 14, P: 1347-1357
IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis

Iuliia O. Peshkova
Aliia R. Fatkhullina
Ekaterina K. Koltsova
ResearchOpen Access23 May 2017
Scientific Reports

Volume: 7, P: 1-14

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Erratum: Activin A programs the differentiation of human T_FH cells

YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution

Nuclear morphology is shaped by loop-extrusion programs

Human coronavirus OC43-elicited CD4⁺ T cells protect against SARS-CoV-2 in HLA transgenic mice

Microfluidics-based side view flow chamber reveals tether-to-sling transition in rolling neutrophils

Bacterial colonization factors control specificity and stability of the gut microbiota

IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis

Neutrophil recruitment limited by high-affinity bent β₂ integrin binding ligand in cis

Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation

Activin A programs the differentiation of human T_FH cells

An integrin αEβ7-dependent mechanism of IgA transcytosis requires direct plasma cell contact with intestinal epithelium

IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis

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