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Showing 1–2 of 2 results
Advanced filters: Author: Ze-Ao Huang Clear advanced filters
  • Treatments to cure chronic hepatitis B (HBV) infection are currently lacking. Here, the authors identify an HBV targeting siRNA that exhibits potent and broad-spectrum antiviral activity in preclinical animal models and demonstrates a favorable safety profile and functional cure indicators, promising clinical translation potential.

    • Ze-Ao Huang
    • Yang Yang
    • Geng-Shen Song
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-15
  • Molecules exhibiting Möbius topology are fascinating but challenging synthetic targets. Here, the authors report the elegant synthesis and crystal structure of a catenane formed from two fully conjugated, interlocked Möbius nanohoops, and use theoretical calculations to understand its conformational stability and aromaticity.

    • Yang-Yang Fan
    • Dandan Chen
    • Huan Cong
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-5