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Advanced filters: Author: Zengyu Gao Clear advanced filters

Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations

In mammals, de novo DNA methyltransferase DNMT3B is essential for establishing DNA methylation patterns during embryonic development. Here the authors provide a structure-function characterization of homo-oligomeric DNMT3B, revealing the molecular basis for its vulnerability to ICF mutations.

Linfeng Gao
Yiran Guo
Jikui Song
ResearchOpen Access22 Jul 2022
Nature Communications

Volume: 13, P: 1-11
Amphioxus adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U and A-to-I deamination of DNA

An adenosine-to-inosine tRNA-editing deaminase ADAT2 from amphioxus (Branchiostoma japonicum) in complex with ADAT3 can perform A-to-I editing of tRNA and convert C-to-U and A-to-I deamination of DNA.

Zhan Gao
Wanyue Jiang
Shicui Zhang
ResearchOpen Access18 Jul 2023
Communications Biology

Volume: 6, P: 1-12
Identification of a locus conferring dominant resistance to maize rough dwarf disease in maize

Ronggai Li
Wei Song
Zengyu Gao
ResearchOpen Access19 Feb 2018
Scientific Reports

Volume: 8, P: 1-10