Nature Search

A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Main-group element-boosted oxygen electrocatalysis of Cu-N-C sites for zinc-air battery with cycling over 5000 h

Balancing the activity and stability of oxygen electrocatalysts is challenging but crucial for rechargeable zinc-air batteries. Here, the authors report a highly active Cu-N-C catalyst boosted by the main-group element for zinc-air battery with a long cycle stability over 5000 h.

Yifan Li
Aijian Huang
Ruitao Lv
ResearchOpen Access27 Sept 2024
Nature Communications

Volume: 15, P: 1-13
An organotypic atlas of human vascular cells

A vascular cell atlas integrating single-cell data of 19 organs and tissues from 62 donors identifies angiotypic and organotypic characteristics of endothelial and mural cells.

Sam N. Barnett
Ana-Maria Cujba
Sarah A. Teichmann
ResearchOpen Access20 Nov 2024
Nature Medicine

Volume: 30, P: 3468-3481
Development and pilot testing of a needs assessment scale for awake patients with tracheal intubation

Mengzhen Liu
Zewen Pan
Xin Liu
ResearchOpen Access06 Nov 2025
Scientific Reports

Volume: 15, P: 1-8
Single-cell multi-omics analysis of the immune response in COVID-19

Transcriptomic and proteomic profiling of blood samples from individuals with COVID-19 reveals immune cell and hematopoietic progenitor cell alterations that are differentially associated with disease severity.

Emily Stephenson
Gary Reynolds
Muzlifah Haniffa
ResearchOpen Access20 Apr 2021
Nature Medicine

Volume: 27, P: 904-916
Integrating transcriptomics and machine learning for immunotherapy assessment in colorectal cancer

Jun Xiang
Shihao Liu
Guiyu Wang
ResearchOpen Access02 Apr 2024
Cell Death Discovery

Volume: 10, P: 1-12
Elite haplotype of STRONG1 enhances rice yield by improving lodging resistance, panicle and plant architecture

Lodging resistance is critical for rice yield. Here, the authors demonstrate that STRONG1 alters the arrangement of the microtubule skeleton, resulting in changes in secondary cell wall development, thereby negatively regulating lodging resistance and grain yield.

Yong Zhao
Jie Gao
Zichao Li
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
Venous-plexus-associated lymphoid hubs support meningeal humoral immunity

Dural-associated lymphoid tissues are lymphoid structures around vascular hubs in the dura mater that sample antigens and rapidly support humoral immune responses after local pathogen challenge.

Zachary Fitzpatrick
Nagela Ghabdan Zanluqui
Dorian B. McGavern
Research20 Mar 2024
Nature

Volume: 628, P: 612-619
Three-dimensional open nano-netcage electrocatalysts for efficient pH-universal overall water splitting

Water electrolysis is considered a key reaction for future sustainable fuel generation. Here, authors report a three-dimensional RuIrOx nano-netcage catalyst that shows high activities and efficiencies for pH-universal overall water splitting.

Zewen Zhuang
Yu Wang
Yadong Li
ResearchOpen Access25 Oct 2019
Nature Communications

Volume: 10, P: 1-10
Electrochemical upcycling of uranyl from radioactive organic wastewater with a self-standing covalent-organic framework electrode

Efficient upcycling of uranyl– containing radioactive organic wastewater is of utmost importance for the sustainable development of nuclear energy. Here, authors proposed an indirect electrochemical method to upcycle uranyl from radioactive organic wastewater.

Huihui Jin
Yezi Hu
Xiubing Huang
ResearchOpen Access15 Apr 2025
Nature Communications

Volume: 16, P: 1-9
Efficient all-thermally evaporated perovskite light-emitting diodes for active-matrix displays

All-thermal evaporation enables the fabrication of green perovskite LEDs with a peak external quantum efficiency of 16.4%, and active-matrix displays with high resolution and continuous greyscale information.

Jinghui Li
Peipei Du
Jiang Tang
Research06 Apr 2023
Nature Photonics

Volume: 17, P: 435-441
Interfacial water engineering boosts neutral water reduction

Understanding the slow kinetics of hydrogen evolution reaction in neutral media is of fundamental importance for the rational design of high-performance electrocatalysts for hydrogen energy. Here, by studying Ru single atom and RuSe_x cluster, the authors report how the rate of hydrogen evolution reaction activity in neutral media is governed by interfacial water.

Kaian Sun
Xueyan Wu
Chen Chen
ResearchOpen Access21 Oct 2022
Nature Communications

Volume: 13, P: 1-11
Ultrastrong conductive in situ composite composed of nanodiamond incoherently embedded in disordered multilayer graphene

In situ composites consisting of nanodiamond homogeneously dispersed in disordered multilayer graphene with incoherent interfaces and complex bonding are synthesized that exhibit an ultrahigh hardness and compressive strength, and excellent electrical conductivity.

Zihe Li
Yujia Wang
Xiaoyan Li
ResearchOpen Access15 Dec 2022
Nature Materials

Volume: 22, P: 42-49
The potential target of bithionol against Staphylococcus aureus: design, synthesis and application of biotinylated probes Bio-A2

Yue Luo
Zewen Wen
Shiqing Han
Research25 Apr 2023
The Journal of Antibiotics

Volume: 76, P: 406-415
A method for reconstructing the dynamic displacement of floating structures based on acceleration measurements and comparison with data-reconstruction techniques

Shujian Gao and co-authors propose a dynamic displacement reconstruction method for floating structures, addressing the challenges posed by the non-contact measurement devices due to the absence of fixed reference points in marine environments.

Shujian Gao
Xi Chen
Fushun Liu
ResearchOpen Access08 Apr 2025
Communications Engineering

Volume: 4, P: 1-15
Single-cell immune repertoire analysis

This Review provides an overview of bioinformatic approaches that enable immune repertoire analyses at the single-cell level.

Sergio E. Irac
Megan Sioe Fei Soon
Zewen Kelvin Tuong
Reviews18 Apr 2024
Nature Methods

Volume: 21, P: 777-792
P4HA2 hydroxylates SUFU to regulate the paracrine Hedgehog signaling and promote B-cell lymphoma progression

Quanfu Li
Yiyang Liu
Wei Jiang
ResearchOpen Access22 Jun 2024
Leukemia

Volume: 38, P: 1751-1763
Unhealthy lifestyle factors and the risk of colorectal cancer: a Mendelian randomization study

Xingyuan Li
Zewen Chang
Qingchao Tang
ResearchOpen Access15 Jun 2024
Scientific Reports

Volume: 14, P: 1-10
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

Shu Zheng
Wei Feng
Chang Shu
ResearchOpen Access20 May 2025
Scientific Reports

Volume: 15, P: 1-14
LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells

Minmin Xiong
Mengshi Wu
Xiaomin Zhong
ResearchOpen Access06 Jan 2021
Cell Death & Disease

Volume: 12, P: 1-17
The sodium/myo-inositol co-transporter SLC5A3 promotes non-small cell lung cancer cell growth

Zihan Cui
Chuanyong Mu
Chun Xu
ResearchOpen Access27 Jun 2022
Cell Death & Disease

Volume: 13, P: 1-12

Search

A benchmark of expert-level academic questions to assess AI capabilities

Main-group element-boosted oxygen electrocatalysis of Cu-N-C sites for zinc-air battery with cycling over 5000 h

An organotypic atlas of human vascular cells

Development and pilot testing of a needs assessment scale for awake patients with tracheal intubation

Single-cell multi-omics analysis of the immune response in COVID-19

Integrating transcriptomics and machine learning for immunotherapy assessment in colorectal cancer

Elite haplotype of STRONG1 enhances rice yield by improving lodging resistance, panicle and plant architecture

Venous-plexus-associated lymphoid hubs support meningeal humoral immunity

Three-dimensional open nano-netcage electrocatalysts for efficient pH-universal overall water splitting

Electrochemical upcycling of uranyl from radioactive organic wastewater with a self-standing covalent-organic framework electrode

Efficient all-thermally evaporated perovskite light-emitting diodes for active-matrix displays

Interfacial water engineering boosts neutral water reduction

Ultrastrong conductive in situ composite composed of nanodiamond incoherently embedded in disordered multilayer graphene

The potential target of bithionol against Staphylococcus aureus: design, synthesis and application of biotinylated probes Bio-A2

A method for reconstructing the dynamic displacement of floating structures based on acceleration measurements and comparison with data-reconstruction techniques

Single-cell immune repertoire analysis

P4HA2 hydroxylates SUFU to regulate the paracrine Hedgehog signaling and promote B-cell lymphoma progression

Unhealthy lifestyle factors and the risk of colorectal cancer: a Mendelian randomization study

HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells

The sodium/myo-inositol co-transporter SLC5A3 promotes non-small cell lung cancer cell growth

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