Nature Search

GDF11 slows excitatory neuronal senescence and brain ageing by repressing p21

How excitatory neurons (EN) acquire senescence is unclear. Here, the authors show that GDF11 in ENs slows EN senescence, brain ageing, cognitive decline and maintains lifespan, revealing a mechanism underlying EN senescence and brain ageing.

Di-Xian Wang
Zhao-Jun Dong
Jing-Wei Zhao
ResearchOpen Access17 Nov 2023
Nature Communications

Volume: 14, P: 1-24
Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro

Bao-lin Chen
Yue-dong Ma
Yu-gang Dong
Research28 Jun 2010
Acta Pharmacologica Sinica

Volume: 31, P: 798-804
Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource

Wei Hu
Qing Yan
Ze-Guang Han
Research14 Sept 2003
Nature Genetics

Volume: 35, P: 139-147
Single-step ambient-air synthesis of graphene from renewable precursors as electrochemical genosensor

Graphene films are commonly produced by thermal chemical vapour deposition, which is capable of producing high-quality films but still limited by factors such as high cost. Here, the authors report the growth of single-to-few-layer continuous graphene films under ambient-air conditions.

Dong Han Seo
Shafique Pineda
Kostya (Ken) Ostrikov
ResearchOpen Access30 Jan 2017
Nature Communications

Volume: 8, P: 1-9
Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing

Age-dependent decline in remyelination in the CNS is associated with declined differentiation capacity of oligodendrocyte progenitor cells (OPCs). Here, the authors show nuclear entry of SIRT2 is impaired and NAD+ levels are reduced during ageing in mouse OPCs. β-nicotinamide mononucleotide (β-NMN) supplement delays myelin aging and enhances remyelination in the aged mice.

Xiao-Ru Ma
Xudong Zhu
Jing-Wei Zhao
ResearchOpen Access09 Mar 2022
Nature Communications

Volume: 13, P: 1-19
Future enhanced threshold effects of wildfire drivers could increase burned areas in northern mid- and high latitudes

Future wildfire dynamics in boreal and temperate ecosystems could depend on threshold effects of climate change-related fire drivers, leading to an increase in burned areas of about 50% by 2100, according to an analysis of climate, vegetation and human activity data.

Hang Zhao
Zhengxiang Zhang
Long Dong
ResearchOpen Access21 Mar 2025
Communications Earth & Environment

Volume: 6, P: 1-13
MnO_x/carbon nanotube/reduced graphene oxide nanohybrids as high-performance supercapacitor electrodes

This work reports a simple and robust approach to integrate MnO_x nanoparticles onto flexible graphite paper using an ultrathin CNT/RGO supporting layer. Supercapacitor electrodes employing the MnO_x/CNT/RGO nanohybrids without any conductive additives or binders yielded a high specific capacitance. The cycling stability of the nanohybrid electrodes was further improved through functionalizing the CNT/RGO supporting layer with atmospheric-pressure plasmas, demonstrating the synergistic use of nanohybrids and plasma-related effects for enhanced device performance.

Zhao Jun Han
Dong Han Seo
Kostya (Ken) Ostrikov
ResearchOpen Access31 Oct 2014
NPG Asia Materials

Volume: 6, P: e140
Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway

Xiao-Ru Ma
Shu-Ying Yang
Jing-Wei Zhao
ResearchOpen Access01 Apr 2022
Cell Death Discovery

Volume: 8, P: 1-15
A novel hepatovirus identified in wild woodchuck Marmota himalayana

Jie-mei Yu
Li-li Li
Zhao-Jun Duan
ResearchOpen Access29 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
MoS₂-coated vertical graphene nanosheet for high-performance rechargeable lithium-ion batteries and hydrogen production

MoS₂-coated vertical graphene nanosheet nanocomposites are successfully designed and synthesized as high-performance electrode materials for both lithium-ion batteries and hydrogen production. The unique three-dimensional hybrid structure is the key to the high performance for energy storage and conversion.

Ye Wang
Bo Chen
Hui Ying Yang
ResearchOpen Access20 May 2016
NPG Asia Materials

Volume: 8, P: e268

Search

GDF11 slows excitatory neuronal senescence and brain ageing by repressing p21

Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro

Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource

Single-step ambient-air synthesis of graphene from renewable precursors as electrochemical genosensor

Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing

Future enhanced threshold effects of wildfire drivers could increase burned areas in northern mid- and high latitudes

MnO_x/carbon nanotube/reduced graphene oxide nanohybrids as high-performance supercapacitor electrodes

Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway

A novel hepatovirus identified in wild woodchuck Marmota himalayana

MoS₂-coated vertical graphene nanosheet for high-performance rechargeable lithium-ion batteries and hydrogen production

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