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Showing 1–3 of 3 results
Advanced filters: Author: Zhaofu Gao Clear advanced filters

  • The oxygenation of deeper continental shelf waters during the Mesoproterozoic coincided with the appearance of multicellular eukaryotes, according to geochemical and sedimentological analyses of the Yanliao Basin, China.

    • Kan Zhang
    • Xiangkun Zhu
    • Simon W. Poulton
    Research
    Nature Geoscience
    Volume: 11, P: 345-350

  • Comprehensive analyses of Cas9 proteins shed light on the evolution of the CRISPR–Cas9 system, and identify a pro-CRISPR accessory protein in bacteria that boosts CRISPR-mediated immunity by enhancing the DNA binding and cleavage activity of Cas9.

    • Shouyue Zhang
    • Ao Sun
    • Jun-Jie Gogo Liu
    Research
    Nature
    Volume: 630, P: 484-492

  • H3K27me3 binding to the EED pocket of the Polycomb repressive complex 2 (PRC2) is required to activate PRC2. An allosteric small-molecule inhibitor of PRC2 was identified that binds to the EED pocket and blocks PRC2 methyltransferase activity in cells.

    • Wei Qi
    • Kehao Zhao
    • En Li
    Research
    Nature Chemical Biology
    Volume: 13, P: 381-388