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Showing 1–2 of 2 results
Advanced filters: Author: Zhi-Zhou Pan Clear advanced filters

  • Catalytic asymmetric conjugate allylation of unsaturated carbonyl compounds is usually difficult to achieve due to competing 1,2-addition. Here, the authors report a copper(I)-catalyzed asymmetric 1,6-conjugate allylation of 2,2-dimethyl-6-alkenyl-4H-1,3-dioxin-4-ones with good scope and high enantioselectivity.

    • Chang-Yun Shi
    • Zhi-Zhou Pan
    • Liang Yin
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10

  • Ming-Rong Wang, Benjamin Berman and colleagues perform whole-exome sequencing and global methylation profiling on different tumor regions of esophageal squamous cell carcinoma. They find evidence for intratumoral heterogeneity and identify late driver mutations targeting oncogenes and early driver mutations occurring in tumor-suppressor genes.

    • Jia-Jie Hao
    • De-Chen Lin
    • H Phillip Koeffler
    Research
    Nature Genetics
    Volume: 48, P: 1500-1507