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Showing 1–13 of 13 results
Advanced filters: Author: Zhiting Xu Clear advanced filters
  • Amines are common targets in synthetic chemistry as they often display biological activity. Here, the authors report a one-pot aminobenzylation of aldehydes with readily available toluenes in presence of a sodium amide derivative and a cesium salt additive generating an array of valuable 1,2-diarylethylamine compounds.

    • Zhiting Wang
    • Zhipeng Zheng
    • Patrick J. Walsh
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-8
  • The pilot phase of PigGTEx, re-analyzing 5,457 published RNA-seq samples, presents a pan-tissue catalog of molecular quantitative trait loci. Cross-species comparisons identify traits with shared genetic regulation in humans.

    • Jinyan Teng
    • Yahui Gao
    • Lingzhao Fang
    ResearchOpen Access
    Nature Genetics
    Volume: 56, P: 112-123
  • The challenges in reliably reproducing the quantum anomalous Hall effect have emerged as a major bottleneck for MnBi2Te4. Here, the authors develop a fabrication method to address this, paving the way for the fabrication of high-quality dissipationless topological transport devices.

    • Yongqian Wang
    • Bohan Fu
    • Chang Liu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-8
  • Low-dielectric-constant (k < 2) materials are needed to reduce crosstalk, delay and power consumption in microelectronic circuits. Here, the authors report the growth of low-k 2D fluoride-rich polymer thin films, showing good mechanical properties and their application for the realization of 2D MoS2 transistors with improved performance.

    • Qiyi Fang
    • Kongyang Yi
    • Jun Lou
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-9
  • MnBi2Te4 is an antiferromagnetic topological insulator. This combination of magnetic ordering and topological properties has resulted in intense interest, however, like many van der Waals materials, experimental results are hampered by fabrication difficulties. Here, Li, Wang, Lian et al. show that the fabrication process itself can result in mismatched thickness dependence of magneto-transport measurements. ‘

    • Yaoxin Li
    • Yongchao Wang
    • Chang Liu
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-9
  • Activation of the NLRP3 inflammasome triggers the production of inflammatory cytokines. Here, the authors inactivate NLRP3 in macrophages using CRISPR/Cas9 encapsulated in nanoparticles, and show that administration in mice is effective in preventing septic shock and peritonitis, and in improving diabetes-associated inflammation and insulin resistance.

    • Congfei Xu
    • Zidong Lu
    • Jun Wang
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14
  • Machine learning methods can predict and recognize binding patterns between T-cell receptors and human antigens, but they struggle with antigens for which no or little data exist regarding interactions with the immune system. A new method called PanPep based on meta-learning can learn quickly on new binding prediction tasks and accurately predicts pairing between T-cell receptors and new antigens.

    • Yicheng Gao
    • Yuli Gao
    • Qi Liu
    Research
    Nature Machine Intelligence
    Volume: 5, P: 236-249
  • Various methods have been proposed to identify synthetic lethality interactions, but selective treatment opportunities for various tumors have not yet been explored. Here, the authors develop the Synthetic Lethality Knowledge Graph webserver (SLKG, http://www.slkg.net) to explore the comprehensive tumor therapy landscape and uncover cancer-specific susceptibilities based on the principle of synthetic lethality.

    • Biyu Zhang
    • Chen Tang
    • Qi Liu
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11