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Showing 1–3 of 3 results
Advanced filters: Author: Zhiyou Su Clear advanced filters

  • Achieving selective and precise modification of macromolecules under biocompatible conditions (such as aqueous solutions, mild temperatures, and neutral pH) remains a significant technical challenge. Here, the authors develop a photoinduced coupling reaction based on N-hydroxy naphthalimide esters, which is effective in biologically relevant conditions.

    • Hongze Liao
    • Zhiyou Su
    • Hou-Wen Lin
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11

  • A truncating variant of 17β-hydroxysteroid dehydrogenase-13 (17β-HSD13), a lipid droplet -associated protein, associates with lower risk of chronic liver disease. Here the authors identify a phosphorylation site in 17β-HSD13 which promotes lipolysis, and report that a knock-in mouse with a 17β-HSD13 mutant defective for phosphorylation is more susceptible to nonalcoholic steatohepatitis.

    • Wen Su
    • Sijin Wu
    • Youfei Guan
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18

  • Unlike with inorganic photocatalysts, the facet-dependent reactivity of conjugated polymers remains elusive. Now, the authors provide molecular-level insights on the reactive facets of crystalline poly(triazine imide) intercalated with LiCl and achieve a remarkable improvement in its overall photocatalytic water splitting activity.

    • Lihua Lin
    • Zhiyou Lin
    • Xinchen Wang
    Research
    Nature Catalysis
    Volume: 3, P: 649-655