Peripheral nerve modulation is promising for regulating physiological functions, but its performance relies on a stable electrode–tissue interface. Here, the authors present a tissue-adaptive bioelectronic fiber that thermo-contracts at body temperature, forming robust biointerfaces. Incorporating carbon nanotubes enables mixed ionic–electronic conductivity, supporting reliable neural stimulation and 99.5% signal retention in sciatic nerve recordings under repeated activation.
- Tao Zhou
- Rouhui Yu
- Shaowu Pan