Nature Search

Identification of causal plasma proteins and targeted therapy for primary hepatic carcinoma via proteome-wide Mendelian randomization

A study utilizing proteome-wide Mendelian randomization identifies 27 proteins linked to primary hepatic carcinoma, highlighting INHBC’s role in tumour progression, while demonstrating ACVR2B blockade’s potential in reducing tumour growth.

Houhong Wang
Kejun Hu
Zhongmin Li
ResearchOpen Access26 Nov 2025
Communications Biology

Volume: 8, P: 1-14
First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial

In a prespecified interim analysis of the randomized, double-blind phase 3 COMPASSION-15 trial, patients with advanced HER2-negative gastric/GEJ cancer treated with the anti-PD-L1/CTLA-4 bispecific Ab cadonilimab plus chemotherapy showed significantly improved overall survival compared with patients treated with placebo plus chemotherapy as first-line treatment.

Lin Shen
Yanqiao Zhang
Jiafu Ji
Research22 Jan 2025
Nature Medicine

Volume: 31, P: 1163-1170
Metallic micronutrients are associated with the structure and function of the soil microbiome

Soil micronutrients may be important for belowground biota and associated functions. Here, the authors identify the relationships between metallic micronutrients and soil microbial communities and functions across 180 sites, and validate them in a soil incubation experiment.

Zhongmin Dai
Xu Guo
Jianming Xu
ResearchOpen Access20 Dec 2023
Nature Communications

Volume: 14, P: 1-12
Author Correction: First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial

Lin Shen
Yanqiao Zhang
Jiafu Ji
Amendments and Corrections26 Mar 2025
Nature Medicine

Volume: 31, P: 1368
Task offloading for multi-server edge computing in industrial Internet with joint load balance and fuzzy security

Xiaomin Jin
Shuai Zhang
Zhongmin Wang
ResearchOpen Access13 Nov 2024
Scientific Reports

Volume: 14, P: 1-26
Multiple environmental stressors interactively affect soil phosphorus cycling microbiomes

Interactive stressors influence microbial-regulated phosphorus cycling and availability in soil by changing the abundance and diversity of phosphorus cycling microorganisms and associated stoichiometric parameters, according to an analysis of soil samples from a large-scale survey across China

Xianjin Tang
Yun Chen
Jianming Xu
ResearchOpen Access22 Sept 2025
Communications Earth & Environment

Volume: 6, P: 1-12
Sensitive responders among bacterial and fungal microbiome to pyrogenic organic matter (biochar) addition differed greatly between rhizosphere and bulk soils

Zhongmin Dai
Jiajie Hu
Jianming Xu
ResearchOpen Access08 Nov 2016
Scientific Reports

Volume: 6, P: 1-11
Long-term nutrient inputs shift soil microbial functional profiles of phosphorus cycling in diverse agroecosystems

Zhongmin Dai
Guofei Liu
Jianming Xu
ResearchOpen Access11 Dec 2019
The ISME Journal

Volume: 14, P: 757-770
Genetic correlation network prediction of forest soil microbial functional organization

Bin Ma
Kankan Zhao
Jianming Xu
ResearchOpen Access25 Jul 2018
The ISME Journal

Volume: 12, P: 2492-2505
Geographic patterns of co-occurrence network topological features for soil microbiota at continental scale in eastern China

Bin Ma
Haizhen Wang
Jack A Gilbert
ResearchOpen Access15 Jan 2016
The ISME Journal

Volume: 10, P: 1891-1901

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