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Showing 1–6 of 6 results
Advanced filters: Author: Zhouyan Guo Clear advanced filters

  • Here, Zhouyan et al. present the structure of yeast SIN3–HDAC complex Rpd3L, revealing a distinctive organization mechanism compared with other class I HDAC complexes. The authors observe that two distinct arms hang on a T-shaped scaffold formed by two coiled-coil domains.

    • Zhouyan Guo
    • Chen Chu
    • Chengcheng Wang
    Research
    Nature Structural & Molecular Biology
    Volume: 30, P: 753-760

  • SWI/SNF remodelers alter histone-DNA interactions and are important for regulating chromatin architecture and gene expression. Here, the authors present the cryo-EM structure of a nucleosome-free Swi/Snf complex from Saccharomyces cerevisiae and discuss the assembly and function of SWI/SNF remodelers.

    • Chengcheng Wang
    • Zhouyan Guo
    • Xiaofeng Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-8

  • In an inter-laboratory study, the authors compare the accuracy and performance of three optical density calibration protocols (colloidal silica, serial dilution of silica microspheres, and colony-forming unit (CFU) assay). They demonstrate that serial dilution of silica microspheres is the best of these tested protocols, allowing precise and robust calibration that is easily assessed for quality control and can also evaluate the effective linear range of an instrument.

    • Jacob Beal
    • Natalie G. Farny
    • Jiajie Zhou
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-29