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Showing 1–3 of 3 results
Advanced filters: Author: Zi-Dong Lu Clear advanced filters

  • Genetic muscle diseases are difficult to treat due to challenges in delivering gene editors to muscles throughout the body. Here, authors engineer muscle-specific virus-like particles that fuse with skeletal muscle cells to deliver CRISPR tools and restore dystrophin in a DMD model.

    • Shi-Kun Zhou
    • Jing-Tong Luo
    • Jun Wang
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12

  • Intratumoral abundance of chemokines, such as CXCL9, is an important driver of T cell infiltration in tumors. Here the authors describe the design of a tumor-specific expression strategy to drive secretion of CXCL9 and an anti-PD-L1 scFv (αPD-L1) in the tumor microenvironment, promoting T cell recruitment and anti-tumor immune response in preclinical cancer models.

    • Yue Wang
    • Shi-Kun Zhou
    • Jun Wang
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • Here the authors provide experimental evidence of extended topological valley-locked states. By splicing together Dirac semimetals and topological insulators, they demonstrate reduced backscattering and enhanced matching of SAW with interdigital transducers proposing this system for topological acoustics devices.

    • Ji-Qian Wang
    • Zi-Dong Zhang
    • Yan-Feng Chen
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8