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Showing 1–3 of 3 results
Advanced filters: Author: Zitong Qiu Clear advanced filters
  • Dysregulation of extracellular matrix (ECM) homeostasis plays a role in the accelerated degradation of cartilage in osteoarthritis (OA). Here the authors engineer an injectable hydrogel based on streamlined-zinc oxide (ZnO), which is responsive to matrix metallopeptidase (MMP), for the delivery of miR-17-5p and show it alleviates cartilage degeneration in a rat model of OA.

    • Wen Li
    • Zhiyuan Shi
    • Nan Li
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18
  • Using whole-genome and whole-exome sequencing, this study identifies eight significantly mutated genes in oesophageal squamous cell cancer, including two genes, ADAM29 and FAM135B, not previously associated with this cancer type.

    • Yongmei Song
    • Lin Li
    • Qimin Zhan
    Research
    Nature
    Volume: 509, P: 91-95
  • The Impact of Genomic Variation on Function Consortium is combining single-cell mapping, genomic perturbations and predictive modelling to investigate relationships between human genomic variation, genome function and phenotypes and will provide an open resource to the community.

    • Jesse M. Engreitz
    • Heather A. Lawson
    • Ella K. Samer
    Reviews
    Nature
    Volume: 633, P: 47-57