Hormonal therapies articles from across Nature Portfolio

Advances in the management of hormone-sensitive prostate cancer have been achieved through intensification of therapy, although careful patient selection is required. In this Review, the authors discuss personalized treatment strategies for both non-metastatic and metastatic hormone-sensitive prostate cancer, as well as emerging novel therapies and key principles for toxicity mitigation.

A new meta-analysis presented at the 2025 American Neurological Association Annual Meeting shows that initiation of hormone replacement therapy in women soon after the onset of menopause is associated with a reduced risk of Alzheimer disease.