Renovascular hypertension articles from across Nature Portfolio

Dietary potassium influences blood pressure. This study shows that excess dietary potassium raises blood pressure via enhanced aldosterone driven ENaC activity. Yet, greater dietary potassium is beneficial to blood pressure when salt intake is high.

Hypertension (HTN) is a major risk factor for cardiovascular disease, stroke, and increased mortality, with significant racial and ethnic disparities in prevalence and control. Non-Hispanic Black (NHB) adults in the United States (US) have the highest rates of HTN compared to other racial and ethnic groups, yet foreign-born NHBs exhibit lower HTN prevalence than their US-born counterparts. This paper explores the role of birthplace, acculturation, and socioeconomic factors in shaping HTN risk among NHBs. Despite higher treatment rates, NHBs face systemic barriers to HTN control, underscoring the need for targeted public health interventions. Emerging evidence suggests that foreign-born NHBs may have healthier dietary patterns, but prolonged residence in the US is associated with increasing HTN prevalence, potentially due to acculturation and lifestyle changes. Understanding these variations is crucial for developing tailored, culturally sensitive strategies to mitigate HTN disparities. Future research should further investigate regional origins, dietary shifts, and healthcare access to inform public health initiatives aimed at improving cardiovascular health outcomes in this high-risk population.

A recent study reports that adenosine A2A receptor-mediated lymphangiogenesis increases lymphatic clearance of excess Na⁺ from the skin and reduces blood pressure, whereas impairment of this process leads to salt-sensitive hypertension. These findings raise intriguing physiological questions regarding the relationships among sodium, water and blood pressure.