Single-channel recording articles from across Nature Portfolio

Latest Research and Reviews

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  Hybrid knowledge- and data-driven modelling for robust spike detection and sorting in human C-fiber microneurography

  • Alina Troglio
  • Andrea Fiebig
  • Barbara Namer

  ResearchOpen Access12 Mar 2026 Scientific Reports

  Volume: 16, P: 8975
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  In vivo acoustoelectric neural recording in mice enabled by ultrasound-induced frequency mixing

  Jean Rintoul and colleagues introduce in vivo acoustoelectric neural recording, using focused ultrasound to recover electrophysiological signals in the rodent brain. This work enables a non-invasive, artefact-robust path toward portable, focal neural recording.

  • Jean L. Rintoul
  • Jonathan Howard
  • Nir Grossman

  ResearchOpen Access10 Feb 2026 Communications Engineering

  Volume: 5, P: 37
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  Closed state structure of the pore revealed by uncoupled Shaker K⁺ channel

  Voltage-gated potassium channels control excitability, but their non-conductive structure remained elusive. Here, authors reveal the Shaker channel’s closed-pore structure, showing distinct “roll-and-turn” helix movements that redefine activation gating in the Kv1 family.

  • Yichen Liu
  • Carlos Bassetto
  • Francisco Bezanilla

  ResearchOpen Access19 Nov 2025 Nature Communications

  Volume: 16, P: 10180
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  Utilizing native nanodiscs to isolate active TRPC3 channels and expand structural analysis capabilities

  • Jasmin Baron
  • Lena Bauernhofer
  • Oleksandra Tiapko

  ResearchOpen Access05 Aug 2025 Scientific Reports

  Volume: 15, P: 28562
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  The plasma membrane inner leaflet PI(4,5)P₂ is essential for the activation of proton-activated chloride channels

  Proton-activated chloride (PAC) channels regulate intracellular Cl^- levels following acidosis in all tissues. Here the authors show that PI(4,5)P₂ of the plasma membrane inner leaflet is essential for the proton activation of PAC channels.

  • Woori Ko
  • Euna Lee
  • Byung-Chang Suh

  ResearchOpen Access15 Aug 2024 Nature Communications

  Volume: 15, P: 7008
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  Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers

  Quantitative characterization of kinase conformational dynamics remains challenging. Here, the authors show that protein nanopore tweezers allow analyzing the conformational energy landscape and ligand binding of the Abl kinase domain.

  • Fanjun Li
  • Monifa A. Fahie
  • Min Chen

  ResearchOpen Access20 Jun 2022 Nature Communications

  Volume: 13, P: 3541