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T-cell lymphomas are a type of non-Hodgkin lymphoma that involve the malignant transformation of T cells. Four major types have been characterized: extranodal T-cell lymphoma, cutaneous T-cell lymphomas (Sézary syndrome and Mycosis fungoides), anaplastic large cell lymphoma and angioimmunoblastic T-cell lymphoma.
Paul and colleagues report the development and characterization of an antibody–drug conjugate targeting TRBC2 for the treatment of T cell malignancies.
