Sir,

Corneal crystalline deposits of immunoglobulin origin have been reported to occur in a variety of hypergammaglobulinaemic states, including multiple myeloma, benign monoclonal gammopathy, cryoglobulinaemia, Waldenström's macroglobulinaemia, rheumatoid arthritis,1 other associated neoplasms,2 and after immunoglobulin therapy.3 The most frequently reported monoclonal gammopathy associated with corneal crystalline deposits is of the IgG-kappa light chain. We report an unusual case, initially presenting with corneal crystalline deposits, who developed IgA-kappa multiple myeloma 2 years later. To the best of our knowledge, only one case of corneal crystalline deposits associated with IgA-kappa monoclonal gammopathy2 has been described in the literature. However, bone marrow pathology of that patient was normal.

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