Sir,

Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a paraneoplastic syndrome described by Machemer1 in 1966, in which an underlying tumor causes diffuse bilateral proliferation of melanocytes in the uvea. Gass et al.2 later described five cardinal signs related to BDUMP: multiple red patches at the level of the RPE, corresponding early hyperfluorescence of these patches on fluorescein angiography, development of multiple pigmented and non-pigmented uveal melanocytic tumors with diffuse thickening of the uveal track, exudative retinal detachment, and rapidly progressive cataracts. Patients affected by BDUMP have a short life expectancy.2 We, however, report a case of BDUMP, which illustrates that long-term survival can occur despite multiple metastases.

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