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Depth of inflammation in Crohn's disease

Nature Reviews Nephrology volume 5, page E2 (2009)Cite this article

An Article Report to this article was published on 01 March 2009

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Arising from: Waters AM et al. (2008) Tubulointerstitial nephritis as an extraintestinal manifestation of Crohn's disease. Nat Clin Pract Nephrol 4: 693–697 [doi:10.1038/ncpneph0955]

I read with interest the article by Waters and colleagues.1 The authors state that Crohn's disease is characterized by mucosal ulcerations; I disagree. The major types of inflammatory bowel disease are ulcerative colitis and Crohn's disease.2 Although the former is a nontransmural inflammatory disorder that is restricted to the colon, the latter is a transmural inflammatory disorder that can affect the entire gastrointestinal tract, and sometimes contribute to fistulas.

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References

  1. Waters AM et al. (2008) Tubulointerstitial nephritis as an extraintestinal manifestation of Crohn's disease. Nat Clin Pract Nephrol 4: 693–697

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  2. Baumgart DC and Sandborn WJ (2007) Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 369: 1641–1657

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  1. Hua Chiew Hospital, Bangkok 10100, Thailand weekitti@gmail.com

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  1. Hua Chiew Hospital, Bangkok, 10100, Thailand

    Weekitt Kittisupamongkol

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  1. Weekitt Kittisupamongkol
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Kittisupamongkol, W. Depth of inflammation in Crohn's disease. Nat Rev Nephrol 5, E2 (2009). https://doi.org/10.1038/ncpneph1044

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  • DOI: https://doi.org/10.1038/ncpneph1044

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