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Cirrhosis

Role of endocannabinoid system confirmed in patients with cirrhosis

Nature Reviews Gastroenterology & Hepatology volume 7, page 417 (2010)Cite this article

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The endocannabinoid system is upregulated in patients with cirrhosis, according to the results of a new study.

Endocannabinoids are involved in various central and peripheral physiological processes. “The endocannabinoid system has captured our attention, as a consistent amount of experimental data has shown that anandamide (AEA), the most important endocannabinoid, is implicated in the pathogenesis of the cardiovascular alterations of cirrhosis,” says Mauro Bernardi, one of the authors of the study.

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ORIGINAL RESEARCH PAPER

  1. Caraceni, P. et al. Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. Liver Int. 6, 816–825 (2010)

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Authors
  1. Isobel Franks
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Franks, I. Role of endocannabinoid system confirmed in patients with cirrhosis. Nat Rev Gastroenterol Hepatol 7, 417 (2010). https://doi.org/10.1038/nrgastro.2010.107

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  • DOI: https://doi.org/10.1038/nrgastro.2010.107

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