Correction to: Acta Pharmacologica Sinica (2022) 44:332–344 https://doi.org/10.1038/s41401-022-00956-w, published online 10 August 2022

The authors would like to apologize for the errors in the previously published images of Fig. 2a. The HE staining in control group presented incorrect accidentally. The inaccuracy was due to an oversight during the preparation of the figures. The authors have carefully checked the raw data and corrected the accidentally confused image. The legend for Fig.1d contains an error regarding the number of mice. It should be changed into“E peak velocity was quantified. n = 7–9.” There is a minor error in the chemical formula of the third compound in Table 1. It should be changed into“C20H21NO4.”

Table 1 Characterization of in vivo metabolites of Tetrahydroberberrubine 1-3 by HPLC/ESI-IT-TOF-MS.

The corrected versions of the affected figures are now presented. It is important to note that these corrections do not alter the findings or conclusions of the paper. The overall interpretation and impact of the study remain unchanged. The authors sincerely apologize for any inconvenience caused to the journal and its readers.

The original article has been corrected.

Revised fig. 2

a Heart tissue specimens were stained with hematoxylin and eosin (HE) (×400). The arrangement of myocardial fibers is marked by a white dotted box, and the rupture of myocardial fibers is indicated by yellow arrows. n = 5. Scale bar: 100 μm. b Heart tissue specimens were stained with Masson trichrome dye (×400). The deposition of collagen fibers is indicated by yellow asterisks. n = 5. Scale bar: 100 μm. c β-gal staining (×200) indicated that THBru delays heart aging. Scale bar: 200 μm.