Extended Data Fig. 9: Liver gluconeogenic metabolite tracing and gene expression profiles.
From: Proline exacerbates hepatic gluconeogenesis via paraspeckle-dependent mRNA retention
a, Isotopologue abundances of liver TCA cycle and gluconeogenesis-related metabolites in liver from ob/ob mice, n = 4 mice. b, mRNA levels of genes associated with inflammation and lipid metabolism in liver from ob/ob or db/db mice, with and without Neat1 activation, ob/ob, n = 5 mice; db/db, n = 7 mice. Data are presented as means ± SD. Statistical significance was determined using a two-tailed Student’s t test in (a) and (b).
