Extended Data Fig. 6: Comparative analysis of metabolomic data across newborn dried blood spots from the COPSAC2010 and COPSAC2000 cohorts. | Nature Metabolism

Extended Data Fig. 6: Comparative analysis of metabolomic data across newborn dried blood spots from the COPSAC2010 and COPSAC2000 cohorts.

From: A western dietary pattern during pregnancy is associated with neurodevelopmental disorders in childhood and adolescence

Extended Data Fig. 6

Comparative analysis of metabolomic data across newborn dried blood spots from the COPSAC2010 and COPSAC2000 mother–child cohorts. Principal Component Analysis (PCA) plots illustrate the distribution and separation of metabolomic data between cohorts. Panels A–C represent overlapping metabolomes used in our analysis (n = 951, n = 774, n = 626), showcasing subsets of metabolites selected based on varying degrees of correlation and distributional similarity between cohorts. A: displays the PCA for metabolites with correlations greater than 0.4 (n = 951), B: Correlations greater than 0.6 (n = 774), and C: Metabolites with a correlation greater than 0.6 passing the two-sample Kolmogorov-Smirnov test with a threshold of >=0.05 (n = 626).

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